Built for a 100+ year life

A science-backed protocol for lasting vitality and elite healthspan

How serious are you
about your health?

The Calicen Protocol is for those who refuse to settle for average health—and who believe longevity should be lived at its highest potential. It is about using the full power of modern science to optimize healthspan and embracing the possibility of living vibrantly well beyond 100 years.

Calicen is the most comprehensive longevity protocol ever designed, created to help you become a thriving centenarian—strong, clear-minded, and full of vitality at every stage of life.

Longevity is more than adding years—it’s about adding life.

Because a long life is just the start. What matters is the quality of that life: to live fully, purposefully, and energetically until the very last day. This is the standard we all deserve.

Calicen brings together cyclical principles of lifestyle, nutrition, movement, and supplementation into one elegant, repeatable 17-week protocol—simple to follow, endlessly sustainable, and designed for a lifetime of renewal.

~~
even the sea
breaths in cycles
~~

~~ eat fiber like a cow ~~

~~ eat omega3 like a dolphin ~~

~~ live life like a water pump ~~

Learn more about
Calicen's Waterpump Principle

How to start?

Reason

Understand the importance of healthspan and longevity. Take a moment for yourself and reflect on your health goals and why it matters. Any health issue? Love for life? Life goal? Identify your motivations.

Commit

Research the Calicen Protocol and commit to the process. This will involve making lifestyle changes, adopting new habits, and prioritizing your health. Commit to yourself fully. Embrace the journey ahead. Fully commit!

Prepare

The protocol comes with a comprehensive kit of supplements. Click on the link and purchase the kit. The kit involves 10 formulas with the exact amount you need for a full cycle of 17 weeks. The kit provides all the supplements for week 1 until week 17. With one purchase you cover the next 4 months.

Start

Begin your first day on the Calicen Protocol. Follow the guidelines for nutrition, exercise, and supplementation as outlined in the protocol. Stay consistent and track your progress throughout the 17 weeks. Congratulations!

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The Protocol
17-week cycle

Pescetarian

Vegan

Mediterranean

purpe|pull

Purge More Intense by the week

From week 1 to week 9 the intensity of the "purging/cleansing/deconstructing and pulling" stimulus becomes stronger. The body gets accostumed by any stimulus. That is why we start with a moderate stimulus and increase the intensity continuously to overcompensate the body's desensibilization. This until we hit maximum stimulus with a 1 week water fast in week 9. Prior to the water fast, protein restriction, calorie restriction and targeted exercising to be used to induce the purging stimulus.

Calorie Restriction

Starting with week 3, we implement calorie restriction to further enhance the purging stimulus. Week 5 until 8 restricts calories even more. Until week 9 we fully restrict calories for a complete week.

Kill Senescent Cells

This is why! Purging of senescent cell is crucial for longevity, rejuvenation and healthspan. Our body must face metobolic stressors like the mentioned calorie restrictions, fasting regimens, protein restriction and exercisies to feel compelled to forcefully engange in the killing of senescent cells. Just feeling alright will not make our body act to necessary degree. We require deep purging to obtain deep autophagy. Homeosttis kills, this is why we must live in the extremes to harvest the specific benefits which each single extrem has to offer. When purging, then we harvest the capacity to get rid of enemy number 1 - bye senescent cells.

grow|push

Fill the gap with "new"

After the intense purging phase, from week 10 to week 17 we focus on rebuilding, repopulating and rejuvenating the body with fresh cells, a diverse microbiome, new muscle tissue and a strong mind. The body is like a sponge after deep cleansing. It soaks up all the nutrients, building blocks and stimuli to grow stronger, healthier and more resilient than ever before.

Microbiome Re-Population

The purge liberated our gut from harmful bacteria and created space for new beneficial bacteria to colonize. From week 10 to week 17 we focus on feeding our microbiome with prebiotics, probiotics and diverse fiber sources to ensure a rich and balanced gut flora. A healthy microbiome is crucial for overall health, immune function and longevity.

Stronger Cycles

With each 17-week cycle, our body becomes more adept at handling the stresses of purging and rebuilding. We can push the boundaries further, inducing deeper autophagy, more effective senescent cell clearance and greater rejuvenation. Over time, these cycles compound, leading to exponential improvements in healthspan and vitality.

nutrition

Macros such as proteins, fats and carbs

Pescetarian

Vegan

Mediterranean

Macros:

Click on the name for more info

The Power of Metabolic Rhythm

Longevity emerges from rhythm, not balance

The human body did not evolve under constant conditions. Growth, repair, fasting, and abundance have always alternated—and our biology still expects this rhythm. Calicen applies this evolutionary truth through the intelligent interplay of carbohydrates, fats, and proteins.

Fats and low carbohydrates shift metabolism toward ketosis, activating AMPK, autophagy, and mitochondrial renewal (Mizushima, 2017; Newman & Verdin, 2014). Reduced protein intake during these phases downregulates mTOR, allowing damaged cells to be cleared rather than endlessly maintained (Blagosklonny, 2006). This is not deprivation—it is precision cleanup.

When carbohydrates and proteins return, the body responds with heightened sensitivity. Insulin signaling, IGF-1, and mTOR are reactivated in a clean metabolic environment, driving muscle growth, tissue repair, and structural resilience (Fontana et al., 2016). What was removed creates space for what is rebuilt.

A homeostatic diet and exercise routine teaches the body to adapt—and then stagnate. Periodization prevents this plateau by alternating signals. Stress followed by recovery. Breakdown followed by construction. Loss followed by gain.

Calicen is not about doing more. It is about timing better. By cycling macros, the protocol restores metabolic flexibility—the defining trait of long-lived organisms—and transforms nutrition into a rhythm that supports strength, regeneration, and longevity well beyond 100.

Carbs & Fats: The Cyclical Balance

Carbs and fats move in opposite directions by design. Low carbs with high fats induce ketosis, favoring cleanup, metabolic flexibility, and cellular pruning. Higher carbs with normalized fats shift the body back into growth mode—supporting muscle gain, regeneration, and performance. This metabolic alternation prevents stagnation: ketosis without wasting, growth without chronic inflammation. In Calicen, carbs and fats work as a coordinated rhythm—one clears the ground, the other builds on it.

Proteins

Protein intake in Calicen follows timing, not dogma. During purge phases, protein is intentionally lowered to reduce mTOR signaling and promote autophagy, cellular recycling, and longevity pathways. In regrowth phases, protein rises to support muscle repair, tissue rebuilding, and structural resilience. This rhythmic approach mirrors natural cycles of breakdown and reconstruction. Protein becomes most effective when delivered at the right moment—after cleanup, when the body is ready to build stronger.

Fats

Fats are the backbone of the purge phase. Elevated fat intake, combined with low carbs, shifts the body toward ketosis—favoring fat oxidation, autophagy, and metabolic efficiency. This phase supports gut rest, inflammation reduction, and the selective loss of dysfunctional or senescent cells. Fats also provide hormonal stability and sustained energy when growth is not the goal. In Calicen, fats are not passive calories—they are tools for deep metabolic renewal.

Carbohydrates

In Calicen, carbohydrates are not constant—they are strategic. During regrowth phases, carbs return to fuel cellular renewal, glycogen restoration, and anabolic signaling. They support thyroid function, training intensity, and microbiome diversity when the body is primed to rebuild. In lower phases, carbs are intentionally reduced to promote metabolic flexibility and deep cellular cleanup. Carbs in Calicen are a signal: when to grow, when to conserve, and when to reset.

	Weeks
Calicen Data Values from previous chart	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Proteins (g/kg)	1.6	1.6	1.3	1.3	1.0	1.0	0.6	0.6	0	2.0	2.0	2.0	2.0	2.0	2.0	1.8	1.8
Carbs (g/kg)	1.5	1.5	0.4	0.4	0.4	0.4	0.4	0.4	0	3.0	3.0	3.0	3.0	3.0	3.0	2.0	2.0
Fats (g/kg)	2.0	2.0	2.4	2.4	2.3	2.3	2.0	2.0	0	1.1	1.1	1.6	1.6	1.6	1.6	1.6	1.6